{"id":31096,"date":"2019-12-31T10:19:34","date_gmt":"2019-12-31T18:19:34","guid":{"rendered":"https:\/\/www.washington.edu\/research\/?page_id=31096"},"modified":"2026-05-29T14:47:56","modified_gmt":"2026-05-29T21:47:56","slug":"changing-external-irb-studies","status":"publish","type":"page","link":"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/changing-external-irb-studies\/","title":{"rendered":"Modify\/Update External IRB Studies"},"content":{"rendered":"<p><img decoding=\"async\" class=\"WP-PrintIcon\" src=\"https:\/\/www.washington.edu\/research\/wp-content\/plugins\/wp-print\/images\/printer_famfamfam.gif\"  alt=\"Print\" title=\"Print\" style=\"border: 2px;\">&nbsp;<a href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/changing-external-irb-studies\/print\/\" title=\"Print\" rel=\"nofollow\" target=\"_blank\">Print<\/a><\/p>\n<div class=\"table-of-contents\">\n<h2 id=\"toc\">Table of Contents<\/h2>\n<ul class=\"list-unstyled\">\n<li><a href=\"#1\">Before You Begin<\/a>\n<ul>\n<li><a href=\"#1a\">What updates does HSD need for external IRB studies?<\/a><\/li>\n<\/ul>\n<\/li>\n<li><a href=\"#2\">Steps for Updating Study Details<\/a><\/li>\n<li><a href=\"#3\">Steps for Site Modifications<\/a><\/li>\n<li><a href=\"#4\">What to Expect After Submitting<\/a><\/li>\n<\/ul>\n<\/div>\n<h2 id=\"1\">Before You Begin<\/h2>\n<h3 id=\"1a\">What updates does HSD need for external IRB studies?<\/h3>\n<p>HSD requires limited ongoing information about externally reviewed studies. For more information:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/how-to-ask-for-a-non-uw-irb\/#during\">External IRB Reliance Process- During the Research<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/checklist-external-irb-uw-researchers\/\">External IRB, UW Researchers Checklist<\/a><\/li>\n<li>Questions? Contact <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a><\/li>\n<\/ul>\n<p><strong>Required Changes for External IRB Studies:\u00a0<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<th scope=\"col\">Change<\/th>\n<th scope=\"col\">How to Initiate<\/th>\n<\/tr>\n<tr>\n<td>Update UW PI<\/td>\n<td>Review <a href=\"\/research\/hsd\/training\/zipline-online-help-library\/change-study-pi\/\">Change Study PI<\/a> Instructions<\/td>\n<\/tr>\n<tr>\n<td>Update Zipline Application Access<\/td>\n<td>Review <a href=\"\/research\/hsd\/training\/zipline-online-help-library\/update-study-team\/\">Update Study Team<\/a> Instructions<\/td>\n<\/tr>\n<tr>\n<td>Change Reviewing IRB<\/td>\n<td>Contact <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> to initiate<\/td>\n<\/tr>\n<tr>\n<td>Planning to Implement E-Consent<\/td>\n<td><strong>Multi-site External Studies:<\/strong><\/p>\n<ol>\n<li>Update <a href=\"#2\">Study Details<\/a> to provide revised External IRB Review Request Form. If the original External IRB Review request form did not include questions about E-Consent, upload the <a href=\"\/research\/forms-and-templates\/supplement-external-econsent\">REQUEST External IRB Addendum eConsent<\/a>.<\/li>\n<li>Create <a href=\"#3\">Site Modification<\/a> (required if you need to add or revise the Other REDCap Installation supplement or Other E-Consent Tools Attestation Letter)<\/li>\n<\/ol>\n<p><strong>Single-site External Studies:<\/strong><\/p>\n<ol>\n<li><a href=\"#3\">Update Study Details<\/a><\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<tr>\n<td>Report Study Closure<\/td>\n<td>Contact <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> to initiate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"2\">Steps for Updating Study Details<\/h2>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 1: Create Study Update in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>In the study workspace, click Update Study Details<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37903 size-medium\" src=\"\/research\/wp-content\/uploads\/Update-Study-Details-244x300.png\" alt=\"screenshot of the update study details button\" width=\"244\" height=\"300\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Update-Study-Details-244x300.png 244w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Update-Study-Details.png 375w\" sizes=\"auto, (max-width: 244px) 100vw, 244px\" \/><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 2: Complete the Study Update Information Form<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>Provide a summary of the update (for example, adding e-consent)<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37900 size-large\" src=\"\/research\/wp-content\/uploads\/Study-Update-Information-1024x413.png\" alt=\"screenshot of the study update information smartform in Zipline\" width=\"1024\" height=\"413\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-1024x413.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-300x121.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-768x310.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-1536x619.png 1536w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-375x151.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-750x302.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information-1140x460.png 1140w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Study-Update-Information.png 1920w\" sizes=\"auto, 100vw\" \/><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 3: Update the Zipline Application<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>You are now in a <em>draft version<\/em> of the study SmartForm and should be on the Basic Study Information page. Update the draft version of the study to reflect any changes being made by making all needed revisions to the SmartForms.<\/p>\n<p><strong>ADDING E-CONSENT:<\/strong><\/p>\n<ul>\n<li><strong>All studies:<\/strong>\n<ul>\n<li>Upload\u00a0the <a href=\"\/research\/forms-and-templates\/supplement-external-econsent\">REQUEST External IRB Addendum eConsent<\/a> on the External IRB SmartForm page.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Multi-site external IRB studies:<\/strong>\n<ul>\n<li>If you need to add the <a href=\"\/research\/forms-and-templates\/supplement-other-redcap-installation\/\">Other REDCap Installation supplement<\/a> and\/or <a href=\"\/research\/forms-and-templates\/template-other-esignature-attestation-letter\/\">Other E-Consent Tools Attestation Letter<\/a> you must submit a Site Modification in addition to the Study Update<\/li>\n<li>If the Local Site Documents page is not available, your study is multi-site in Zipline<\/li>\n<\/ul>\n<\/li>\n<li><strong>Single-site external IRB studies:<\/strong>\n<ul>\n<li>Upload the <a href=\"\/research\/forms-and-templates\/supplement-other-redcap-installation\/\">Other REDCap Installation supplement<\/a> or <a href=\"\/research\/forms-and-templates\/template-other-esignature-attestation-letter\/\">Other E-Consent Tool Attestation Letter<\/a> on the Local Site Documents page<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>To Add a Document: <\/strong><\/p>\n<ul>\n<li>Click Add<\/li>\n<li>Select the new document from your computer<\/li>\n<li>Click OK in the Edit Attachment window<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37893 size-large\" src=\"\/research\/wp-content\/uploads\/Add-document-1024x188.png\" alt=\"screenshot of the add document button in Zipline\" width=\"1024\" height=\"188\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-1024x188.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-300x55.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-768x141.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-375x69.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-750x138.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document.png 1118w\" sizes=\"auto, 100vw\" \/><\/p>\n<p><strong>To <\/strong><strong>Update a Document:<\/strong><\/p>\n<ul>\n<li>If needed, click the ellipsis by the document<\/li>\n<li>Click Upload Revision or Update<\/li>\n<li>Select the revised file from your computer<\/li>\n<li>Click OK in the Edit Attachment window<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-45411 size-full\" src=\"\/research\/wp-content\/uploads\/upload-revised-external-irb.png\" alt=\"screenshot of clicking the ellipsis to upload a revision of the external IRB request form\" width=\"936\" height=\"300\" \/><\/p>\n<p><strong>To Remove a Document:<\/strong><\/p>\n<ul>\n<li>Click the X by the document<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37895 size-large\" src=\"\/research\/wp-content\/uploads\/delete-document-1024x237.png\" alt=\"screenshot of the delete document button in Zipline\" width=\"1024\" height=\"237\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-1024x237.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-300x69.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-768x178.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-375x87.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-750x173.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-1140x264.png 1140w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document.png 1150w\" sizes=\"auto, 100vw\" \/><\/p>\n<p>Click Save and Exit out of the draft SmartForm once your changes are complete<\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 4: Email <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> when the update is complete<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>\u2022 HSD staff will finalize the update after your change has been assessed.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"3\">Steps for Site Modifications<\/h2>\n<p>This activity is only available for multi-site external studies<\/p>\n<div class=\"accordion \" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 1: Create Site Modification in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>In the study workspace, click Create Site Modification<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-45413 size-full\" src=\"\/research\/wp-content\/uploads\/Create-site-modification.png\" alt=\"screenshot of the create site modification button in Zipline\" width=\"256\" height=\"300\" \/><\/p>\n<ul>\n<li>Indicate that the purpose of the submission is Modification\/Update<\/li>\n<li>Indicate the modification scope (can select both options)\n<ul>\n<li>UPDATING ZIPLINE ACCESS: See <a href=\"\/research\/hsd\/training\/zipline-online-help-library\/update-study-team\/\">Update Study Team<\/a> for detailed instructions<\/li>\n<li>ADDING E-CONSENT: Select \u201cOther Parts of the Site\u201d<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37897 size-large\" src=\"\/research\/wp-content\/uploads\/modification-purpose-scope-1024x412.png\" alt=\"screenshot of the modification purpose scope in Zipline\" width=\"1024\" height=\"412\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-1024x412.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-300x121.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-768x309.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-1536x617.png 1536w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-375x151.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-750x301.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope-1140x458.png 1140w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/modification-purpose-scope.png 1921w\" sizes=\"auto, 100vw\" \/><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 2: Complete the Modification Information page<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>Add a summary of the changes<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37899 size-large\" src=\"\/research\/wp-content\/uploads\/site-modification-summary-1024x492.png\" alt=\"screenshot of the site modification summary smartform in Zipline\" width=\"1024\" height=\"492\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-1024x492.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-300x144.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-768x369.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-1536x738.png 1536w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-375x180.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-750x361.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary-1140x548.png 1140w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/site-modification-summary.png 1893w\" sizes=\"auto, 100vw\" \/><\/p>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 3: Update the Zipline Application<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>You are now in a <em>draft version<\/em> of the site SmartForm and should be on the Basic Local Site Information page. Update the draft version of the site to reflect any changes being made by making all needed revisions to the SmartForms.<\/p>\n<p><strong>ADDING E-CONSENT:<\/strong><\/p>\n<ul>\n<li>A site modification is only required if you need to upload the Other REDCap Installation Supplement or the Other E-Consent Tools Attestation Letter to the Local Site Documents page.<\/li>\n<li>If not already done, update Study Details with the revised External IRB Review Request on the External IRB SmartForm page<\/li>\n<\/ul>\n<p><strong>To Add a Document:<\/strong><\/p>\n<ul>\n<li>Click Add<\/li>\n<li>Select the new document from your computer<\/li>\n<li>Click OK in the Edit Attachment window<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37893 size-large\" src=\"\/research\/wp-content\/uploads\/Add-document-1024x188.png\" alt=\"screenshot of the add document button in Zipline\" width=\"1024\" height=\"188\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-1024x188.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-300x55.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-768x141.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-375x69.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document-750x138.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/Add-document.png 1118w\" sizes=\"auto, 100vw\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>To <\/strong><strong>Update a Document:<\/strong><\/p>\n<ul>\n<li>If needed, click the ellipsis by the document<\/li>\n<li>Click Upload Revision or Update<\/li>\n<li>Select the revised file from your computer<\/li>\n<li>Click OK in the Edit Attachment window<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37902 size-large\" src=\"\/research\/wp-content\/uploads\/update-document-local-sites-1024x213.png\" alt=\"screenshot of the update document button in Zipline\" width=\"1024\" height=\"213\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites-1024x213.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites-300x63.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites-768x160.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites-375x78.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites-750x156.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/update-document-local-sites.png 1123w\" sizes=\"auto, 100vw\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><strong>To Remove a Document:<\/strong><\/p>\n<ul>\n<li>Click the X by the document<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37895 size-large\" src=\"\/research\/wp-content\/uploads\/delete-document-1024x237.png\" alt=\"screenshot of the delete document button in Zipline\" width=\"1024\" height=\"237\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-1024x237.png 1024w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-300x69.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-768x178.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-375x87.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-750x173.png 750w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document-1140x264.png 1140w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/delete-document.png 1150w\" sizes=\"auto, 100vw\" \/><\/p>\n<ul>\n<li>Click Save and Exit\/Finish to exit the SmartForm<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Step 4: PI or PI Proxy Must Submit<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li>Complete the Submit activity to send the modification to HSD for review<\/li>\n<\/ul>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-37901 size-medium\" src=\"\/research\/wp-content\/uploads\/submit-site-mod-225x300.png\" alt=\"screenshot of the submit site modification button in Zipline\" width=\"225\" height=\"300\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/submit-site-mod-225x300.png 225w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/submit-site-mod.png 359w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><\/p>\n<\/div>\n<\/div>\n<\/div>\n<h2 id=\"4\">What to Expect After Submitting<\/h2>\n<h3>Study Updates<\/h3>\n<p>An HSD staff member will be assigned to the study update as the IRB coordinator. They will communicate with you as needed about the update.<\/p>\n<p>You may check the status at any time in the update workspace in Zipline. Once the update is finalized, the status will change to Updates Complete in Zipline.<\/p>\n<h3>Site Modifications<\/h3>\n<p>An HSD staff member will be assigned to the site modification as the IRB coordinator. The PI, any PI proxies, and the primary contact will receive email notifications:<\/p>\n<ul>\n<li>If HSD staff need additional information or changes to authorize the modification<\/li>\n<li>When your modification has been authorized<\/li>\n<\/ul>\n<p>You may check the status at any time in the modification workspace in Zipline. Once the modification is authorized, the study status will change to Pending sIRB Review in Zipline.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-img aligncenter wp-image-30800 size-full\" src=\"\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review.png\" alt=\"screenshot of Pending sIRB Review state\" width=\"928\" height=\"169\" srcset=\"https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review.png 928w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review-300x55.png 300w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review-768x140.png 768w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review-375x68.png 375w, https:\/\/www.washington.edu\/research\/wp-content\/uploads\/2019\/11\/Submitting-New-Studies-After-Initial-Approval-Pending-sIRB-Review-750x137.png 750w\" sizes=\"auto, 100vw\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Table of Contents Before You Begin What updates does HSD need for external IRB studies? Steps for Updating Study Details Steps for Site Modifications What to&#8230;<\/p>\n","protected":false},"author":158,"featured_media":0,"parent":11143,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"templates\/page-builder-units-small-hero.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-31096","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Modify\/Update External IRB Studies - UW Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.washington.edu\/research\/hsd\/study-activities\/changing-external-irb-studies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Modify\/Update External IRB Studies - UW Research\" \/>\n<meta property=\"og:description\" content=\"Table of Contents Before You Begin What updates does HSD need for external IRB studies? 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