{"id":68283,"date":"2026-05-29T08:33:41","date_gmt":"2026-05-29T15:33:41","guid":{"rendered":"https:\/\/www.washington.edu\/research\/?page_id=68283"},"modified":"2026-06-01T09:01:04","modified_gmt":"2026-06-01T16:01:04","slug":"irb-reliances","status":"publish","type":"page","link":"https:\/\/www.washington.edu\/research\/hsd\/irb-reliances\/","title":{"rendered":"IRB Reliances"},"content":{"rendered":"<p>First, determine which IRB review pathway applies. Review these resources for guidance or consult with <a href=\"mailto:hsdrely@uw.edu\">hsdrely@uw.edu<\/a> if you are unsure.<\/p>\n<ul>\n<li><strong>For collaborative research with regional institutions:<\/strong>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/oncology-related-research\/\">Cancer-related research with Fred Hutch or other Cancer Consortium members<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/research-involving-fred-hutch-not-cancer-related\/\">Research involving Fred Hutch that is not cancer-related<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/research-involving-seattle-childrens\/\">Seattle Children\u2019s<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/#regional\">Other regional institutions<\/a><\/li>\n<\/ul>\n<\/li>\n<li><strong>For industry research: <\/strong><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/industry-sponsored-research\/\">Industry Sponsored Research<\/a><\/li>\n<li><strong>For other institutions: <\/strong><a href=\"\/research\/hsd\/irb-reliances\/identify-the-correct-irb\/\">Identify the Correct IRB<\/a><\/li>\n<li><strong>For projects where UW is the lead site or coordinating center for multi-institutional research: <\/strong><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/selecting-single-irb\/\">Selecting the Single IRB<\/a><\/li>\n<\/ul>\n<h2>Requesting Review from an External (Non-UW) IRB<\/h2>\n<div class=\"accordion non-bold\" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Process Overview<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>High level process overview of external IRB applications, including getting started, applying to the external IRB, and requirements during the research:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/how-to-ask-for-a-non-uw-irb\/\">External IRB Reliance Process<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Prepare to Apply<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>When UW will be a participating site in a multi-site study:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-participating-site\/\">UW as a participating site in a multi-site study<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/transfers-of-irb-oversight-and-pi-institutional-affiliation-changes\/\">Transferring your UW studies to a new IRB<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Submit in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>When you are ready to submit a request to rely on an external IRB:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/study-activities\/request-authorization-non-uw-irb-reviewing\/\">Request Authorization- External IRB Reviewing\u00a0<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Update\/Modify\/Close<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Obtaining approval from an external IRB and understanding your responsibilities during the life of the study:<\/p>\n<ul>\n<li><a href=\"\/research\/forms-and-templates\/checklist-external-irb-uw-researchers\/\">External Studies Researcher Checklist<\/a><\/li>\n<li><a href=\"\/research\/policies\/guidance-consent-elements-externally-reviewed-studies\/\">Consent Elements for Externally Reviewed Studies<\/a><\/li>\n<\/ul>\n<p>Managing studies that have been authorized to rely on a non-UW IRB:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/study-activities\/changing-external-irb-studies\/\">Update\/Modify\/Close External IRB studies<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Application Forms<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<ul>\n<li><a href=\"\/research\/forms-and-templates\/external-irb-review\/\">Request External IRB Review<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/supplement-dct\/\">Diversity Plan for Clinical Trials Supplement<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/supplement-external-econsent\">Request External IRB Addendum eConsent<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/supplement-other-redcap-installation\/\">Other REDCap Installation Supplement<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/template-other-esignature-attestation-letter\/\">Other E-Consent Tool Attestation Letter Template<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<h2>Requesting UW IRB Review for Non-UW Institutions (including Single IRB)<\/h2>\n<div class=\"accordion non-bold\" id=\"accordion\">\n<div class=\"screen-reader-text\"><\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Process Overview<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>High level process overview of initial applications where UW is reviewing for non-UW institutions:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-irb-as-a-single-irb\/steps-in-the-single-irb-review-process-for-initial-applications\/\">UW as a Single IRB- Initial Application Process<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Prepare to Apply<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>For general information about policies and procedures for single IRB:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/\">Single IRB Overview and Requirements<\/a><\/li>\n<\/ul>\n<p>For specific instructions on how to plan for the use of a single IRB at the pre-award stage:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-irb-as-a-single-irb\/\">UW as the Single IRB<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/\">UW IRB as the Lead or Coordinating Site<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/selecting-single-irb\/\">Selecting the Single IRB<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/cost-single-irb-review\/\">Cost of Single IRB Review<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/letters-support-single-irb\/\">Letters of Support for Single IRB<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/setting-single-irb-arrangement\/\">Setting Up the Single IRB Arrangements<\/a><\/li>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-lead-coordinating-site\/responsibilities-lead-study-team\/\">Responsibilities of the Lead Study Team<\/a><\/li>\n<\/ul>\n<p>For UW specific information when UW will serve as the single IRB:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-irb-as-a-single-irb\/\">UW as the Single IRB<\/a><\/li>\n<li><a href=\"\/research\/policies\/guidance-key-info-uw-sirb\/\">Key Information about UW as the Single IRB guidance<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Submit in Zipline<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Submit an application to the UW IRB requesting review on behalf of other institutions:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/study-activities\/apply-for-review-uw-reviewing-for-other-institutions\/\">Apply for Review- UW Reviewing for Other Institutions<\/a><\/li>\n<li><a href=\"\/research\/hsd\/study-activities\/add-relying-sites\/\">Add Relying Sites to Approved Study<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Modify\/Renew\/Report\/Close<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Manage the study and relying sites once approved by the UW IRB:<\/p>\n<ul>\n<li><a href=\"\/research\/hsd\/irb-reliances\/single-irb\/uw-irb-as-a-single-irb\/steps-in-the-single-irb-review-process-follow-ons\/\">UW as the Single IRB- Renew, Modify, Report, Close Processes<\/a><\/li>\n<li><a href=\"\/research\/hsd\/study-activities\/modify-multi-institutional-study\/\">Modify Approved Multi-institutional Study<\/a><\/li>\n<li><a href=\"\/research\/hsd\/study-activities\/renew-or-close-multi-institutional-study\/\">Renew or Close Approved Multi-institutional Study<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"card\">\n<div class=\"card-header\" id=\"accordion-header\">\n<h3 class=\"mb-0\"><button class=\"btn btn-link\" type=\"button\" data-toggle=\"collapse\" data-target=\"#collapse\" aria-expanded=\"false\" aria-controls=\"collapse\"><span class=\"btn-text\">Application Forms<\/span><span class=\"arrow-box\"><span class=\"arrow\"><\/span><\/span><\/button><\/h3>\n<\/div>\n<div id=\"collapse\" class=\"collapse \" aria-labelledby=\"collapse\" data-parent=\"#accordion\" role=\"region\">\n<p>Study Forms:<\/p>\n<ul>\n<li><a href=\"\/research\/forms-and-templates\/zipline-application-irb-protocol\/\">IRB Protocol Form<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/zipline-application-irb-protocol-no-contact-with-subjects\/\">IRB Protocol, No Contact with Subjects Form<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/supplement-multi-site-or-collaborative-research\/\">Multi-site or Collaborative Research Supplement<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/supplement-non-uw-individual-investigators\/\">Non-UW Individual Investigators Supplement<\/a><\/li>\n<\/ul>\n<p>Site Forms:<\/p>\n<ul>\n<li><a href=\"\/research\/forms-and-templates\/site-app-contact\/\">Site Application (Contact)<\/a><\/li>\n<li><a href=\"\/research\/forms-and-templates\/site-app-no-contact\/\">Site Application (No Contact)<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>First, determine which IRB review pathway applies. Review these resources for guidance or consult with hsdrely@uw.edu if you are unsure. For collaborative research with regional institutions:&#8230;<\/p>\n","protected":false},"author":15,"featured_media":0,"parent":274,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"templates\/page-builder-units-small-hero.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-68283","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>IRB Reliances - UW Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.washington.edu\/research\/hsd\/irb-reliances\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IRB Reliances - UW Research\" \/>\n<meta property=\"og:description\" content=\"First, determine which IRB review pathway applies. 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